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Fabrication of novel material with athrombogenic potential: Immobilization of peptides on polyurethane surface

Fabrication of novel material with athrombogenic potential: Immobilization of peptides on polyurethane surface
File Size:
201.57 kB
Author:
Paulina Ziętek, Beata Butruk, Tomasz Ciach
Email:
paulina[dot]zietek[at]wp[dot]pl
Date:
13 August 2013
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Abstract: Presented study was undertaken to fabricate a hemocompatible material that could be a potential candidate for use in fabrication of blood-contacting devices, e.g. circulatory support devices, vessel grafts, heart valves. Th e fi nal material could be used as a scaff old for endothelial cell growth and initiate in situ endothelialisation. Th e newest and most promising strategy in material endothelialization involves introduction of short peptide sequences that can selectively address one particular type of cell adhesion receptors and promote cell adhesion. Th us, the aim of work was to elaborate a method of immobilizing peptides specific for integrins onto polymer substrate.

Keywords: polyurethane, endothelium, peptides immobilization

Area: Nanotechnologies and Materials

BibTeX:

@article{Zietek2012,
  author = {Paulina Ziętek and Beata Butruk and Tomasz Ciach},
  title = {Fabrication of novel material with athrombogenic potential: Immobilization of peptides on polyurethane surface},
  journal = {Challenges of Modern Technology},
  year = {2012},
  volume = {3},
  number = {1},
  pages = {38--41},
  url = {http://www.journal.young-scientists.eu/index.php/isuues/file/77-fabrication-of-novel-material-with-athrombogenic-potential-immobilization-of-peptides-on-polyurethane-surface}
}
 
 

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